Sculptra vs. Radiesse: Redefining Facial Rejuvenation in 2025

two facial spa professionals performing facial injections

When pursuing long-term results that appear effortless and refined, many clients are moving away from traditional fillers and exploring collagen boosters. While hyaluronic fillers are still popular, a new category of injectables has gained attention in recent years: Biostimulators. These are not your typical dermal fillers; they are collagen-boosting powerhouses designed to improve your skin’s foundation over time. In today’s industry, two names dominate this space: Sculptra and Radiesse.

If you’re debating which option might be best for you, continue reading as we break down the differences and help you find the perfect match.

What Is Sculptra?

Sculptra is powered by poly-L-lactic acid (PLLA), a biostimulator that gently activates your skin’s natural collagen production. Sculptra injections are subtle and buildable, avoiding the instant plumpness typical of most hyaluronic fillers. Instead, results emerge gradually, revealing firmer, fuller, and more youthful skin that looks like a refined version of you. It doesn’t scream “filler,” but it provides that natural, refreshed appearance that many desire.

Our Sculptra treatment is ideal for clients noticing early signs of aging, facial hollowness, or loss of elasticity in areas like the cheeks, temples, and jawline. It serves as an internal facial approach, restoring soft volume while improving overall skin health. Results can last up to two years, sometimes longer, making it a favourite for those invested in long-term skin health rather than quick fixes.

Reforme Lab Blogs professional facial injections

What is Radiesse?

On the other hand, Radiesse offers different properties and delivers different results. It provides a dual impact by offering immediate volume while initiating a collagen-building response through its calcium hydroxylapatite (CaHa) microspheres. Think of it as a treatment that combines structure and skin quality. Clients leave their appointments with clear contouring in the jawline, chin, and mid-face, seeing further improvements over the following months.

Radiesse is popular among clients seeking definition and lift, particularly in the lower face. It’s also a great option for non-surgical facial sculpting, providing a sharper, more contoured profile that doesn’t move or migrate over time like dermal fillers.

Which Treatment Do I Choose?

So, what’s the real difference between the two? It comes down to pace, placement, and goals. Sculptra injections embody the “slow and steady wins the race” approach, perfect for those seeking overall skin rejuvenation, subtle volume, and youthful features that develop naturally over time. Although there’s no instant gratification, the results after 2-3 months are always worth the wait, offering longevity, skin integrity, and ultra-natural results that enhance with each session.

Conversely, Radiesse caters to clients desiring immediate effects and quicker results. If you’re looking for more definition in the jawline, cheekbones, or chin area while benefiting from collagen stimulation, Radiesse could be an excellent choice. In skilled hands, it can effectively contour the face without the downtime associated with surgery.

As with any treatment, both options have their minimal downsides. Unlike traditional dermal fillers, neither treatment can be corrected or dissolved, making them non-reversible. Therefore, it’s crucial to choose an experienced and skilled injector to ensure precision.

woman getting facial injections at a beauty clinic

Explore the Options with Ease

If you’re ready to explore the world of collagen biostimulators and step away from traditional dermal fillers, consider this your invitation to embrace the next generation of facial rejuvenation.